12 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology Gitelman ... Syndrome is a rare ... gene that encodes thiazide-sensitive ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
SAME, Cushing Syndrome ... Absent: Loop and thiazide ... diuretics, Bartter syndrome ... , Gitelman syndrom ... potassium #low #nephrology
Diagnostic criteria of Gitelman syndrome!
#Diagnosis #Nephrology #Gitelman #Syndrome #Criteria
Diagnostic criteria ... of Gitelman syndrome ... #Diagnosis #Nephrology ... #Gitelman #Syndrome ... #Criteria
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
- Thiamine Deficiency ... to longstanding thiamine ... is Korsakoff's syndrome ... #diagnosis #comparison ... #neurology
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Encephalopathy - Acute B1 (Thiamine ... Diagnosis - Caine Criteria ... - Intravenous thiamine ... development of Korsakoff syndrome ... Diagnosis #Management #neurology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
transporter Bartter syndrome ... ascending limb Gitelman ... syndrome - Thiazide-sensitive ... tubule Liddle syndrome ... Defects #Kidney #Nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... affecting the thiazide-sensitive ... gene - Encodes thiazide-sensitive ... patients with thiazide ... #nephrology #management
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Aldosterone: Cushing syndrome ... excess, Liddle syndrome ... Loop diuretics, Thiazide ... , Gitelman syndrome ... algorithm #diagnosis #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
major sweating • Thiazide ... reabsorptive defect) • Thiazide ... furosemide-like lesion) • Gitelman ... reabsorption at the thiazide-sensitive ... Diagnosis #Causes #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Diuretics (loop/thiazide ... Hypomagnesemia • Barrter's/Gitelman's ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology