23 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(LTBI) Pathophysiology ... Diagnosis: Latent ... Treatment: Active ... #TB #Diagnosis ... #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(LTBI) Pathophysiology ... Diagnosis: Latent ... Treatment: Active ... #TB #Diagnosis ... #Management #Treatment
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in Tuberculosis ... - Diagnosis and ... Management Summary ... decreased reflexes Pathophysiology ... #TB #Diagnosis
Tuberculin Skin Test Interpretation - Threshold for treatment
Induration cutoff >5mm:
 • Recent exposure to an individual
Threshold for treatment ... individual with active TB ... consistent with old TB ... individuals #Tuberculosis ... SkinTest #TST #diagnosis
IDSA - Clinical Strategy to Build an Individualized Treatment Regimen for Multi-Drug Resistant Tuberculosis (MDR-TB)
 •
Individualized Treatment ... Multi-Drug Resistant Tuberculosis ... are contacts of infectious ... #MDRTB #management ... #Treatment #antimicrobials
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Auto-amplification loop Diagnosis ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis ... #management #treatment
Hansen's Disease (Leprosy)
 • Transmission - not completely understood, ?nasal droplets
 • Symptoms appear ~5 years
and borderline tuberculoid ... and numerous AFB Treatment ... x 24 m BIDMC Infectious ... Disease #Leprosy #diagnosis ... #management #treatment
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
Mycobacterium Tuberculosis ... Infection and Disease ... and molecular diagnostic ... Mycobacterium #Tuberculosis ... #Treatment #management
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management ... polymicrobial infection ... Lung Abscess Pathophysiology ... westermani • Other: TB ... #treatment #diagnosis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of a previously diagnosed ... No specific diagnostic ... (<100), except TB ... TB - Lymphadenitis ... #Management