5 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Disease, PRES Pathophysiology ... permeability Diagnosis ... #neurology #rheumatology ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Auto-amplification loop Diagnosis ... salmonella, ...), Parasites ... #management #treatment ... #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
cell lymphoma Pathophysiology ... histopathologic changes in LNs ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis ... #management #rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... especially the CNS ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... #Management #Infections