21 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • Differentiate ... #Joint #Pain #SickleCell ... #diagnosis #causes ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... • Bone marrow ... #Diagnosis #Management ... #treatment #hematology ... #oncology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... • Bone and joint ... Diagnosis: ... Rule out other causes ... #diagnosis #management
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Bone/Joint Causes ... Limb ischemia • Aortic ... refill - Poor pulses ... differential #diagnosis
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
is caused by a ... Examine for: • Pulse ... deficit/differential ... #Dissection #diagnosis ... #management #vascular
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Diagnosis Framework ... HEMATOLOGIC ... #differential # ... diagnosis #cancer
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential ... Fever/Chills/Joint ... pain/Night sweats ... Loss of signal pulses ... - Aneurysmal bone
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Rheumatic fever • Aortic ... Diminished peripheral pulses ... #pain #differential ... #diagnosis #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... Hypocellular/Hypoplastic MDS ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... pain, fever, joint ... pain, bleeding, ... #Leukemia #Hematology ... #Oncology #Diagnosis