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diagnosis rheumatology cardiology endocarditis erythematosus management signs symptoms arteritis classification conditions dermatology extrarticular gca giantcell infectiousdiseases joint monoclonal nonpalpable oncology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Butterfly rash, Vasculitis ... Endocarditis, Aortic ... ) Blood (75%): Anemia ... #SLE #systemic
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemic skin lesions ... lupus erythematosus ... diminished, or tender pulses ... , and SLE) • Urinalysis ... #rheumatology #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... hemorrhagic skin lesions ... - Hemolytic anemia ... Associated - SLE ... #Diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... papulosquamous lesions ... permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... #Systemic #Lupus
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... < 30 years • Aorta ... claudication, pulse ... Arteritis): • Aorta
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Lyme disease, Vasculitis ... Rheumatic fever • Aortic ... Diminished peripheral pulses ... #joint #pain #differential ... #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... (-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
CA • Involves aortic ... • Autoimmune (SLE ... Marantic (NTBE) Differential ... valvular disease • Vasculitis ... Leukocytosis, anemia
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... those coming off aorta ... very remarkable w/differential ... complaints- anemia ... required due to skip lesions
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
- Overview and Differential ... Ovarian CA, involves aortic ... • Autoimmune (SLE ... valvular disease • Vasculitis ... Leukocytosis, anemia
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