10 results
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... ischemia - Skin: erythematous ... systemic lupus erythematosus ... purpura: strong sign ... diminished, or tender pulses
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... Endocarditis, Aortic ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... < 30 years • Aorta ... claudication, pulse ... Arteritis): • Aorta ... ischemia • Skin: Erythematous
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
• Ischemia of optic ... Leakage of optic ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... those coming off aorta ... systemic sx + signs ... = vasculitis vs ... required +/- prompt ophthalmology
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
- Differential Diagnosis ... meningeal irritation signs ... headache • CNS Vasculitis ... #differential #diagnosis ... #ophthalmology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
after CRAO -> Pale Optic ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Takayasu’s Arteritis: Pathogenesis and clinical findings

 - Fatigue, weight loss, low grade fever, arthralgias
 - Incr
, CRP, WBC - Aortic ... potential for aortic ... Decr palpable pulses ... Takayasus #Arteritis #Vasculitis ... #Diagnosis #Signs
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... • Bilateral signs ... for brain and/or optic ... - Sjogren - Vasculitis