12 results
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Petechial/Purpuric ... Patients with petechiae ... Those with petechiae ... patients with petechiae ... #Petechiae #Purpural
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Skin Findings: • Petechiae ... , Palpable purpura ... sensation or pain: • Petechiae ... • Palpable purpura ... Henoch-Schönlein purpura
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Small Vessel: Petechiae ... , Palpable purpura ... Vasculitis: - Ig A (HSP ... Vasculitis: • Behcet Disease
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
poor nutrition Clinical ... cramping Skin: • Petechia ... • Purpura • Perifollicular ... • Petechiae, purpura ... Henoch-Schonlein purpura
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura ... purpura: Strong ... purpura • Pauci ... purpura, joint ... purpura (lower
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
easy bruising to purpura ... mucosal bleeding (Petechial ... or purpuric rash ... 5000 to 10,000 ng/mL ... Syndrome #Diagnosis #Management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Manifestations of DIC: • Petechiae ... • Purpura • ... Palpable variants ... Hemorrhagic bullae • Purpura
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Henoch-Schönlein Purpura ... - Symmetric palpable ... purpura mainly ... - Systemic disease ... HenochSchonleinPurpura #HSP
Primary Dermatological Lesions
Primary lesions are physical changes in the skin considered to be caused directly by
directly by the disease ... PETECHIAE and PURPURA ... : Petechiae are ... Purpura are larger ... and may be palpable
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... rash, Vasculitis, Purpura ... Aseptic necrosis of hip ... pain (20%) Renal disease ... erythematosus #signs