10 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Skin Findings: • Petechiae ... , Palpable purpura ... sensation or pain: • Petechiae ... • Palpable purpura ... Henoch-Schönlein purpura
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Small Vessel: Petechiae ... , Palpable purpura ... Vasculitis: - Ig A (HSP ... #dermatology #rheumatology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
poor nutrition Clinical ... cramping Skin: • Petechia ... • Purpura • Perifollicular ... • Petechiae, purpura ... Henoch-Schonlein purpura
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
easy bruising to purpura ... mucosal bleeding (Petechial ... or purpuric rash ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Manifestations of DIC: • Petechiae ... • Purpura • ... Palpable variants ... Hemorrhagic bullae • Purpura
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Henoch-Schönlein Purpura ... - Symmetric palpable ... purpura mainly ... HenochSchonleinPurpura #HSP ... #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura ... purpura: Strong ... purpura • Pauci ... purpura, joint ... purpura (lower
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... rash, Vasculitis, Purpura ... Aseptic necrosis of hip ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
multiforme-like lesions, palpable ... purpura, Pathergy ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Strongyloides Stercoralis
EPIDEMIOLOGY - ASSOCIATED WITH SOUTHEASTERN U.S.:
 • 0-6% US Prevalence of those:
 • ~30% Asymptomatic
contact, farming CLINICAL ... distension, fever, petechia ... /purpura, cough, ... Stercoralis #diagnosis #management