9 results
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... Pathophysiology: ... Palpable: 1) If ... Dermatology #Rash #Petechiae ... #Purpura #Palpable
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Skin Findings: • Petechiae ... , Palpable purpura ... sensation or pain: • Petechiae ... • Palpable purpura ... Henoch-Schönlein purpura
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Small Vessel: Petechiae ... , Palpable purpura ... Vasculitis: - Ig A (HSP
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
poor nutrition Clinical ... cramping Skin: • Petechia ... • Purpura • Perifollicular ... • Petechiae, purpura ... Henoch-Schonlein purpura
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Manifestations of DIC: • Petechiae ... • Purpura • ... Palpable variants ... Hemorrhagic bullae • Purpura
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Pathogenesis and Clinical ... endothelial cells - Palpable ... or necrotic purpura ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... easy bruising to purpura ... mucosal bleeding (Petechial ... or purpuric rash ... 5000 to 10,000 ng/mL
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Henoch Scholein Purpura ... Pathogenesis and Clinical ... and ankles) #HSP ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... multiforme-like lesions, palpable ... purpura, Pathergy ... Behcet syndrome (Clinical ... diagnosis #management #signs