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Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Petechial/Purpuric ... ) purpura occurs ... Nonpalpable purpura ... coagulopathy (DIC), or TTP ... purpura.
Management of Immune Thrombocytopenia (ITP) . 

#Idiopathic #Thrombocytopenic #Purpura #Immune #Thrombocytopenia #ITP #Management #Hematology
(ITP) . ... #Purpura #Immune ... #Thrombocytopenia ... #ITP #Management ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Platelet ... : ITP • Secondary ... disease - DIC/TTP ... Defects: • DIC, TTP
Thrombotic Thrombocytopenic Purpura (TTP) vs Disseminated Intravascular Coagulation (DIC)
#Diagnosis #TTP #DIC #Comparison #Table #Laboratory #Findings #RebelEM
Thrombotic Thrombocytopenic ... Purpura (TTP) vs ... ) #Diagnosis #TTP ... #DIC #Comparison ... Findings #RebelEM #Thrombocytopenia
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Idiopathic Thrombocytopenic ... Purpura Clinical ... Splenectomy #ITP ... #Purpura #Thrombocytopenia ... Diagnosis #Overview #Hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
for workup of thrombocytopenia ... TTP/HUS indicates ... thrombotic thrombocytopenic ... purpura/hemolytic ... , Hematology 2012
Causes of Purpura - Differential Diagnosis
Non-PalpabIe → Palpable
 • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... → Palpable • ... Thrombocytopenia ... (HIT, ITP/HUS), ... BrighamChiefs #Purpura
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP ... implications : TTP ... confirmatory testing for TTP ... #purpura #TTP # ... #Comparison #Diagnosis
Algorithm for the outpatient management of thrombocytopenia. 
(DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
management of thrombocytopenia ... uremic syndrome; ITP ... = immune thrombocytopenic ... purpura; TTP = ... purpura.)
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) ... Diagnosis of TTP ... • Distinguish TTP ... #Purpura #management ... #treatment #rheumatology