15 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... purpura (16%) ... purpura • Vesicles ... overlying purpuric ... Henoch-Schönlein purpura
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Palpable Purpura ... Henoch Schonlein Purpura ... on tuberculosis treatment ... #Purpura #Henoch ... #photo #dermatology
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Thrombocytopenic Purpura ... Clinical: • ... Intracranial hemorrhage Management ... Thrombocytopenic #Purpura ... Thrombocytopenia #Diagnosis
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic Purpura ... (TTP) Diagnosis ... Thrombocytopenic #Purpura ... #management #treatment ... #rheumatology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Petechiae • Purpura ... • Palpable variants ... Hemorrhagic bullae • Purpura ... #management #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... Syndrome: • Clinical ... triad of Palpable ... purpura, Arthralgia ... Henoch-Schönlein purpura
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
, causes and management ... cryoglobulinemia vasculitis Clinical ... involvement with purpura ... neuropathy Treatment ... #Management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... multiforme-like lesions, palpable ... purpura, Pathergy ... Arthritis, AS Treatment ... #management #signs
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
poor nutrition Clinical ... • Petechia • Purpura ... • Petechiae, purpura ... Henoch-Schonlein purpura ... vasculitis Treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
easy bruising to purpura ... (Petechial or purpuric ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology