12 results
Causes of Purpura - Differential Diagnosis
Non-PalpabIe → Palpable
 • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... → Palpable • ... HIT, ITP/HUS), Coagulation ... BrighamChiefs #Purpura ... #Causes #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Platelet ... Acute Infectious Purpura ... OF PALPABLE PURPURA ... Ig A vasculitis/HSP
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Henoch Schonlein Purpura ... Rash: - Purpura ... Complete blood count coagulation ... Diagnosis #Algorithm #Causes
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... , Palpable purpura ... • Palpable purpura ... Vesicles overlying purpuric ... Henoch-Schönlein purpura
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
areas of the body Purpura ... Purpura due to vasculitis ... is usually palpable ... Wet purpura is the ... #Purpura #Bruise
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Manifestations of DIC: • Petechiae ... • Purpura • ... Palpable variants ... Hemorrhagic bullae • Purpura ... #treatment #management
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Small Vessel: Petechiae ... , Palpable purpura ... Vasculitis: - Ig A (HSP
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura ... purpura: Strong ... purpura • Pauci ... purpura, joint ... purpura (lower
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Henoch-Schönlein Purpura ... - Symmetric palpable ... purpura mainly ... HenochSchonleinPurpura #HSP ... Rheumatology #Peds #Pediatrics
Primary Dermatological Lesions
Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... PETECHIAE and PURPURA ... : Petechiae are ... Purpura are larger ... and may be palpable