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diagnosis hematology dermatology differential blood nonpalpable product purpura reactions syndrome vasculitis activation algorithm behcet causes classification clinical coagulation cryoglobulinemia cryoglobulins
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
Petechial/Purpuric ... in vasculitic diseases ... rash, the diagnosis ... lesions may have idiopathic ... #Purpuric #Rash
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Platelet ... Thrombocytopenia: ITP ... Ig A vasculitis/HSP ... #rheumatology #
Henoch Schonlein Leg Rash - Palpable Purpura Purpura: Low Platelets or Vasculitis? 45 years old, seen in our
- Palpable Purpura ... Palpable purpura ... Tip: To differentiate ... #photo #dermatology ... #HSP
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
purpura (16%) ... purpura • Vesicles ... overlying purpuric ... Henoch-Schönlein purpura ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
easy bruising to purpura ... (Petechial or purpuric ... rash) • Heart, ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis: • Purpura ... purpura: Strong ... purpura • Pauci ... purpura, joint ... purpura (lower
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... Clinical triad of Palpable ... purpura, Arthralgia ... • Autoimmune diseases ... Henoch-Schönlein purpura
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Petechiae • Purpura ... • Palpable variants ... Hemorrhagic bullae • Purpura ... • Severe Liver Disease ... causes #treatment #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
multiforme-like lesions, palpable ... purpura, Pathergy ... : Arterial (MCC-small ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Post Transfusion Purpura ... (PTP): Occurs 7 ... Causes purpura & ... Transfusion #diagnosis #management
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