12 results
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Henoch Schonlein Purpura ... Rash: - Purpura ... #Petechiae #Rash ... Diagnosis #Algorithm #Causes
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Acute Purpura Fulminans ... (purpura fulminans ... system failure, purpura ... #Purpura #Fulminans ... #Skin #Rash #clinical
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... , Palpable purpura ... • Palpable purpura ... Vesicles overlying purpuric ... Henoch-Schönlein purpura
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dogs & latter can cause ... gram-negative bacillus cause ... +purpuric rash → ... purpura fulminans ... #dermatology #clinical
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
easy bruising to purpura ... mucosal bleeding (Petechial ... or purpuric rash ... 5000 to 10,000 ng/mL ... #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Manifestations of DIC: • Petechiae ... • Purpura • ... Palpable variants ... Hemorrhagic bullae • Purpura
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura ... purpura: Strong ... purpura • Pauci ... purpura, joint ... purpura (lower
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... Syndrome: • Clinical ... triad of Palpable ... purpura, Arthralgia ... Henoch-Schönlein purpura
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis: • Purpura ... Henoch Schonlein Purpura ... erythematous nodules, purpura ... purpura: strong ... purpura.
Capnocytophaga
GNR with long fusiform shape.  Fastidious facultative anaerobe that grows slowly and needs enriched agar
C.
Capnocytophaga GNR ... = most common cause ... cats) Classic clinical ... shock with fever, rash ... can evolve to purpura