7 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... Proteinuria often ... Nephrotic yndrome—podocyte ... diabetes)) #Glomerular ... #Classification
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria and/or proteinuria ... the patient have glomerular ... #Syndrome #Comparison ... #Algorithm #Nephrology
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... Diseases Nephrotic ... • Injury to podocytes ... formation #Glomerular ... #nephrotic #comparison
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria, proteinuria ... immune deposits in glomeruli ... nephropathy, lupus nephritis ... Glomerulonephritis #RPGN #Classification
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... proteinuria. ... clusters because nephritic ... #Algorithm #differential ... #proteinuria #nephrotic
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... range) proteinuria ... Differential #Diagnosis #Algorithm
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
SLE Hallmark = proteinuria ... severity (ISN/RPS classification ... therapy Goal: proteinuria ... by 12 months Classification ... Focal LN (<50% of glomeruli