27 results
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
ANKH gene, Incr pyrophosphate ... dihydrate (CPPD ... activity, reduces pyrophosphate ... and/or x-ray - CPPD ... Chondrocalcinosis #Pseudogout #CPPD
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Deposition Disease (CPPD ... Think About CPPD ... Asymptomatic CPPD ... monoarticular CPPD ... #Pseudogout #CPPD
Lung Ultrasound in COVID 19 symptoms and a history of COPD

FAMUS @FAMUSultrasound

#Lung #Ultrasound #COVID19 #POCUS #COPD
and a history of COPD ... Ultrasound #COVID19 #POCUS ... #COPD #Algorithm
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... == CPPD == Think ... About CPPD When ... Pathophysiology: • Pyrophosphate ... Asymptomatic CPPD
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
Reduce risk of COPD ... Initiate if severe COPD ... Dosing: 250 mcg tablet ... the treatment of COPD ... #Pharmacology #COPD
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm
Pericardial
 • Effusion
 • Cardiac Tamponade*
 • Constriction
Myocardial
 •
Artery Disease • Stable ... • Asthma • COPD ... Pneumonia • ARDS • COPD
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease

 - Acute CPPD precipitation into the joint space ->
Chondrocalcinosis: Calcium Pyrophosphate ... Dihydrate (CPPD ... Disease - Acute CPPD ... Chondrocalcinosis #Pseudogout #CPPD
Peritoneal Dialysis vs Hemodialysis - Advantages and Disadvantages 
Peritoneal Dialysis:
 • Access: Abdominal wall insertion of
every 6 hours (CAPD ... machine (8 hours) (CCPD ... Hemodialysis #comparison #table
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
e.g. pneumonia, COPD ... Differential #Diagnosis #Table
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
nephrocalcinosis • CPPD ... • Inorganic pyrophosphate ... PPi (inorganic pyrophosphate