12 results
Rheumatoid Arthritis
Rheumatoid Arthritis (RA) is an inflammatory autoimmune condition. While chiefly thought of as a joint
arthritis #TNF #CRP #RANKL ... #ostoblast #Citrullinated
Bone resorption and the relationship between osteoblasts and osteoclasts.  
RANK is expressed on the osteoclasts,
RANK is expressed ... RANKL is expressed ... The binding of RANKL ... to RANK stimulates ... RANK = receptor
Synthesis, metabolism and functions of vitamin D. PTH parathyroid hormone, FGF-23 fibroblast growth factor-23, RANKL receptor
growth factor-23, RANKL
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Factor (RF), Cyclic Citrullinated
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
anti-CCP (cyclic citrullinated
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
-> Anti-Cyclic Citrullinated
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
ccheck EBER (+ in ANKL
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
RF) and cyclic citrullinated
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Rheumatoid factor, anti-citrullinated
Pharmacologic Options for Hypercalcemia Associated with Cancer
Rehydration with NS followed by loop diuretics
 • IV normal
Denosumab - Inhibits RANKL