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hematology anemia differential algorithm blood hemolysis management product reactions agglutinin causes cold disease disorders laboratory maha microangiopathic microscopy pancytopenia platelet
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... LDH Peripheral smear ... Anemia #Laboratory #Testing ... #workup #diagnosis ... #hematology #hemolysis
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... coagulation and other testing ... #anemia #Hematology ... #Pathology #Smear
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... thrombocytopenia - DIC ... #Differential #Diagnosis ... #Algorithm #workup ... #hematology #testing
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... MAHA: TTP, HUS, DIC ... Peripheral Blood Smear ... #hematology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
: CBC with diff, ... acid, peripheral smear ... ↑ Destruction (hemolysis ... #Algorithm #hematology ... #workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... Positive Coombs testing ... IgM) • Blood smear ... - RBC agglutination ... #anemia #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... Peripheral blood smear ... schistocytes, nucleated RBCs ... #Workup #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... , HIV/HCV testing ... #Causes #Workup ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... pain, dark urine, DIC ... false negatives on testing ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... Hyperkalemia: Citrate in RBCs ... false negatives on testing ... RBCs (stored at ... #Transfusion #diagnosis
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