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Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Urinalysis >3 RBCs ... of UTI, urine WBCs ... (proteinuria, RBC ... casts, dysmorphic RBCs ... Workup #urology #blood
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm Blood ... / Normochromic RBCs ... TIBC, Hypochromic RBCs ... Decreased RBC ... Disorder • RBC
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... serum due to the RBCs ... Clinical #Path #Blood ... Smear #Microscopy #RBC
Red cell autoagglutination is the process whereby red cells clump together forming aggregates. This is seen
individual’s red blood ... cells (RBCs or ... serum due to the RBCs ... Clinical #Path #Blood ... Smear #Microscopy #RBC
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
(MCV): Average RBC ... among size of RBCs ... wide range of RBC ... in peripheral blood ... High in acute blood
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Algorithm Normal Blood ... Neutrophils - Low RBC ... Pernicious Anemia RBCs ... Cells, Normal WBCs
Plasmodium falciparum life cycle 1: Mosquito bite, transmission of sporozoite 2: Liver, Asexual replication. 1 sporozoite → 10-30,000
merozoites 3: Blood ... Merozoites infect RBC ... RBC ruptures releasing ... Merozoites infect other RBCs
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... 3) Internal (RBC ... - Peripheral Blood ... Smear ↑ abnormal RBCs
Plasmodium Falciparum Blood Smear. Key features suggesting Plasmodium falciparum: - extreme parasitemia - normocytic RBCs (vivax, ovale prefer big
Plasmodium Falciparum Blood ... parasitemia - normocytic RBCs ... multiples per RBC ... P.f. but rare in blood ... Plasmodium #Falciparum #Blood
ABO Blood Types and Transfusion Compatibility Table A Blood Type: • RBC Antigens: A • Antibodies: Anti-B
ABO Blood Types ... Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens ... Type: • RBC Antigens
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