24 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... - CHAMPS Mnemonic ... glomerulonephritis, type ... 1 (50%-80%), type ... @AnnKumfer #Hypocomplementemia
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
Types of hypersensitivity ... reactions Type ... (Anaphylaxis) Type ... II - IgG or IgM ... Serum Sickness) Type
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... II - IgG or IgM ... Cell-bound antigen - IgG ... IgG can also mediate ... Type Ill - IgG and
Cryoglobulinemia Classification Types

Type 1: Monoclonal IgM (rarely IgG/lgA)
 • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Classification Types ... IgM (rarely IgG ... and polyclonal IgG ... and polyclonal IgG ... and polyclonal IgG
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... node), high serum IgG4 ... rheumatoid factor), ± hypocomplementemia ... with increased IgG4 ... Mettler_K1000 #IgG4
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Mediator: IgM + IgG ... Graves' Disease Type ... Immunological Mediator: IgG
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of types ... Type 1 - Mediators ... Eczema, Asthma Type ... - Mediators: IgG ... Mechanism of Action: IgG
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
IGG-4 RELATED DISEASE ... infiltration of IgG4 ... lesions - IgG4 ... • Pancreas: Type ... Biliary Tract: IgG4
Treatment of Non-hepatitis C virus Cryoglobulinemia Vasculitis - French Vasculitis Study Group

MONOCLONAL CRYOGLOBULINEMIA (TYPE 1) 
IgM
CRYOGLOBULINEMIA (TYPE ... chloraminophene IgG ... CRYOGLOBULINEMIA (TYPES
RN-CHAMPS Mnemonic for Types of Shock

R - Respiratory - Flail Chest, Tension Pneumothorax, Pleural Effusion, Hypoxemia
RN-CHAMPS Mnemonic ... for Types of Shock ... Endocarditis #Shock #RNCHAMPS