13 results
Algorithm showing a stepwise approach to the assessment and investigation of a possible neuropathy. CIDP, chronic
of a possible neuropathy ... GBS, Guillain-Barré ... syndrome; HNPP, ... #Diagnosis #Neurology ... #Neuropathy #Peripheral
Ramsay Hunt Syndrome - Herpes Zoster Oticus 
Triad:
1. Ipsilateral facial paralysis 
2. Ear pain 
3. Vesicles
Ramsay Hunt Syndrome ... meningitis • Peripheral ... motor neuropathy ... Encephalitis • Guillain-Barré ... syndromes #
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Etiologies of Peripheral ... Neuropathy • Metabolic ... CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... diagnosis #causes #neurology
Guillain-Barre Syndrome
An acute polyneuropathy (disorder Of the peripheral nervous System).
Symptoms are Often symmetrical and progress Over
Guillain-Barre Syndrome ... disorder Of the peripheral ... GuillainBarre #Syndrome ... #Diagnosis #Neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Criteria for Guillain Barre ... Required for Guillain-Barré ... botulism, toxic neuropathy ... #criteria #neurology ... #neuropathy
Mechanisms of Pain
Mixed - Nociceptive/Neuropathic
Nociceptive - Tissue Damage
 - Visceral - (From organ/cavity lining) Poorly localized,
- Nociceptive/Neuropathic ... longer duration Neuropathic ... lancinating - Peripheral ... regional pain syndrome ... Pain #Mechanisms #Neurology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Causes of Peripheral ... Neuron and Motor Neuropathy ... Multifocal Motor Neuropathy ... Lambert-Eaton Myasthenic Syndrome ... #Weakness #Neurology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Miller Fisher Syndrome ... #Syndrome #diagnosis ... management #treatment #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... cross-reacts with peripheral ... or the axon of peripheral ... the underlying pathophysiology ... #Syndrome #diagnosis
NPSLE - Neurological and Psychiatric Manifestations of Systemic Lupus Erythematosus
 • Central: Aseptic meningitis, Cerebrovascular disease,
Demyelinating syndrome ... , Psychosis • Peripheral ... : Guillain-Barre ... syndrome, Autonomic ... gravis, Cranial neuropathy