855 results
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA ... cause TYPE IV RTA ... , TYPE I RTA Diagnosis ... Sjogrens #Syndrome #Rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... ribonucleoprotein) • RA ... topoisomerase I), RNA ... Autoantibodies #Rheumatology
Renal Tubular Acidosis - Diagnosis Algorithm
 • Hyperkalemic Type 4 RTA
 • Hypokalemic Type 1 RTA
Hyperkalemic Type 4 RTA ... Hypokalemic Type 1 RTA ... • RTA of renal ... Proximal Type 2 RTA ... #RTA #Renal #Tubular
Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology #
Renal Tubular Acidosis (RTA) Diagnosis and Management
 • Distal (type 1) RTA
 • Proximal (type 2)
Tubular Acidosis (RTA ... Distal (type 1) RTA ... Proximal (type 2) RTA ... Hyperkalemic (type 4) RTA ... #rta #Renal #Tubular
Renal Tubular Acidosis (RTA) 
Type 1 - Failure of secretion
Type 2 - Bicarbonate wasting
Type 4 -
Tubular Acidosis (RTA ... juvenile distal RTA ... Tubular #Acidosis #RTA
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
with PLEX and RTX ... management #treatment #rheumatology ... #hematology
Renal tubular acidosis (RTA): refers to a group of conditions all of which cause the same
tubular acidosis (RTA ... types/causes of RTA ... Diagnosis #IM #Nephro #RTA
Urine Anion Gap in NAGMA
NA + K - Cl = surrogate for Urine NH4+
NH4+ is excreted
distrubances - Proximal RTA ... imparied: - Distal RTA ... - Type 4 RTA
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Inflammatory Conditions: Rheumatologic ... ATRA, TPO, TPO-RA ... Diagnosis #Algorithm #hematology