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diagnosis hematology management chronic cll hemeonc lymphocytic alcoholic algorithm anemia anthracycline aplastic cardiology cardiotoxicity chemotherapy emergencies hepatitis her2 mds myelodysplasia
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... transformation) Treatment ... Progressive bore marrow failure ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... microglobulin Treatment ... • Bone marrow failure ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... and petechiae Causes ... Inherited marrow-failure ... virus (EBV) • Leukemia ... Aplastic #Anemia #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Bone Marrow Failure ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Syndromes #diagnosis #hematology ... #oncology
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Eligibility for Treatment ... exclude other causes ... - Acute kidney injury ... - Multiorgan failure ... Management #Algorithm #hepatology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Treat underlying cause ... Usually myeloid leukemias ... → no immediate treatment ... hypotension, renal failure
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity Anthracyclines cause cardiomyopathy: ✖ Reduction in left ventricular ejection fraction
20%, or if heart failure ... ) and initiate treatment ... for heart failure ... detection of cardiac injury ... improve or heart failure
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