11 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
(ACLF) Clinical ... months without treatment ... Lung Failure ... Drug-Induced Liver Injury ... #Cirrhosis #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
acid metabolism products ... = nonspecific (nausea ... → Acute liver failure ... Maternal Support - Critical ... Liver #Pregnancy #hepatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
hypoTN, renal failure ... Causes purpura & ... Related Acute Lung Injury ... TRALI): Leading cause ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... without other cause ... : 33% • Treatment ... CVP, left heart failure ... Transfusion #Reactions #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Highly variable clinical ... to acute liver failure ... pattern of liver injury ... regarding need for treatment ... Diagnosis #Management #Hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... Fibrin degradation products ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
hypoTN, renal failure ... Causes purpura & ... Related Acute Lung Injury ... TRALI): Leading cause ... diagnosis #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Marrow (Toxic injury ... Aplastic Anemia Clinical ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... Hodgkin Lymphoma - Clinical ... genes and gene products ... Hodgkin Lymphoma Treatment ... classification #hematology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Eligibility for Treatment ... exclude other causes ... - Acute kidney injury ... - Multiorgan failure ... Management #Algorithm #hepatology