19 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... vonWillebrand #Syndrome ... #Diagnosis #Management ... #treatment #hematology
STEMI Equivalents on ECG
 • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
Equivalents on ECG ... point • De Winter syndrome ... Deeply inverted anterior ... Acute ischemia in LVH ... #EKG #diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Symptoms (DRESS) Syndrome ... Methylprednisolone 0.5 - 1.5 mg/kg ... BrighamChiefs #DRESS #Syndrome ... #Treatment #Management ... #dermatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... involvement: May involve anterior ... antiinflammatory properties e.g ... Rheumatology #diagnosis #management ... #Dermatology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Cytokine Activation Syndrome ... Tocilizumab 4-8mg/kg ... Siltuximab 11mg/kg ... Siltuximab #COVID19 #Pharmacology ... #Management #Medications
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... underlying disease (eg ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... of diagnosis (e.g ... papules, nodules; anterior ... • Heerfordt syndrome ... Sarcoidosis #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Encephalopathy Syndrome ... Clinico-Radiological Syndrome ... on MRA/CTA • Anterior ... • EEG: With persistent ... #diagnosis #management