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differential disease management vasculitis classification pain workup activation amyloid amyloidosis approach autoimmune behcet behcets conditions criteria cryoglobulinemia cryoglobulins dermatology erythematosus
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Neurologic system ... disease, Vasculitis (e.g ... #differential #diagnosis ... #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
organ or nerve root ... present both at rest ... osteopetrosis, avascular ... #Pain #MSK #rheumatology ... #differential #diagnosis
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
- Diagnosis Diagnostic ... Abnormal pathergy test ... vasculitis) • Arthritis ... , medium-large joints ... #criteria #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... and diplopia) • Vascular ... Positive pathergy test ... is a skin prick test ... signs #symptoms #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... idiopathic arthritis ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... (to support a diagnosis ... laboratory #workup #diagnosis ... #testing #Rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... Diagnosis: ... antiinflammatory properties e.g ... blockers had the best ... #Rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Joint pain • Swan ... arthropathy • 90% joints ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Vascular Sludging ... Labs/Diagnosis: ... . systemic lupus ... classification #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... pulse deficits vascular ... eruption • Joints ... Palpable purpura, joint ... #Rheumatology
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