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Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
the peripheral blood ... TTP/HUS indicates ... purpura/hemolytic ... , Hematology 2012 ... #Evaluation
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... intravascular coagulation (DIC ... purpura (TTP), ... syndrome (HUS) ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /TTP/HUS - Hemolytic ... Diagnosis #hematology ... #rheumatology # ... #dermatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... - MAHA: TTP, HUS ... , DIC, HELLP ... Urobilinogen #Hemolysis ... Diagnosis #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... • Acute Hemolytic ... Hemolysis on labs ... #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Febrile Non-Hemolytic ... - Acute Hemolytic ... Hemolysis on labs ... #diagnosis #management ... #hematology #reactions
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... • Palpable variants ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology