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differential nephrology management treatment blood hematology hypokalemia hypomagnesemia pharmacology product reactions rhabdomyolysis algorithm binders binding classification comparison diuresis diuretics drugs
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... patients sensitive to high ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Renal Loses - Medications ... #Differential #Diagnosis ... Low #Magnesium #Table ... Classification #Causes ... #Workup #hypomg
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... Medications 2. ... #causes #potassium ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... Medications 2. ... #causes #potassium ... #high #nephrology
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
- Insulin (high ... hypomagnesemia #Medications ... #differential #diagnosis ... #nephrology #Causes ... #hypomg
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
Causes of Hyperkalemia ... - Differential Diagnosis ... hyperosmolality - Medications ... #Causes #potassium ... #high
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Management Summary Causes ... - Endocrine: Hypo ... Monitor potassium ... #Management #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... only if no clear cause ... Elimination (see Table ... #Treatment #potassium
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
- Differential Diagnosis ... etc), Endocrine (Hypo ... Monitor potassium ... Dialysis for severe hyperkalemia ... Management #Summary #causes
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic ... urine Na/Cl < 0.7, high ... correcting serum potassium ... Other medications ... continued in most cases
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