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diagnosis hematology differential cryoglobulinemia gammopathy hodgkins lymphoma mgus significance cell clinical comparison cryoglobulins gap globulin management mds myelodysplasia myelodysplastic nonhodgkins
Cryoglobulinemia Classification Types Type 1: Monoclonal IgM (rarely IgG/lgA) • Raynaud phenomenon, Digital ulcers/gangrene, Livedo reticularis, Hyperviscosity
Cryoglobulinemia Classification ... : Monoclonal IgM ... 2: Monoclonal IgM ... Cryoglobulinemia #Classification ... #Types #hematology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... immunotactoid GN, Type ... ASanchez_PS #Monoclonal ... Differential #Diagnosis #hematology ... #oncology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... Cryoglobulins: - Single monoclonal ... - Composed of monoclonal ... #classification ... #rheumatology #
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... categorized into 3 sub-types ... level (non-IgM type ... #Significance #hematology ... #diagnosis #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
translocation • Types ... : Classification ... on: - Cell type ... NonHodgkins #comparison #oncology ... #differential #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... Hodgkin Lymphoma Workup ... lymphoma #diagnosis #classification ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... One blood cell type ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... it represents a monoclonal ... Causes of Monoclonal ... endocrinopathy, monoclonal ... Comment on type
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
tissue composed of monoclonal ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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