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diagnosis algorithm causes management albumin lfts saag transaminitis druginduced gastroenterology gradient aclf acute aflp chemistry chronic drug failure fatty function
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... and Type of Liver ... Injury #Medications ... #Differential # ... #LiverInjury #Hepatology
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 Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... • NAFLD • Cirrhosis ... (>1000): • DILI ... injury) • Ischemic ... #Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... dose dependent injury ... or symptoms of liver ... #differential # ... gastroenterology #hepatology
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
Diagnosis of ascites ... protein ≤ 2.5 g/dL: Cirrhosis ... syndrome, Massive liver ... albumin #gradient #hepatology ... #differential #
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... involvement, Kidney injury ... disorder (e.g. ascites ... #Injury #Diagnosis ... #Algorithm #hepatology
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... #Differential # ... Diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... those with CLD (± cirrhosis ... Injury (DILI) ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... of ascites removed ... • Acute kidney injury ... Indications #Management #Cirrhosis ... #treatment #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... hepatitis: < 1 • Cirrhosis ... #differential # ... diagnosis #algorithm #hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
- Differential ... - Hepatic: • Cirrhosis ... disease • Acute liver ... #Differential # ... Diagnosis #Algorithm #Hepatology
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