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diagnosis treatment cardiology differential fusarium infections infective microbiology negative algorithm aspergillus bcnie bloodculture bloodcultures candida candidemia cglabrata fungal fungemia glabrata
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
with Infective Endocarditis ... therapy - Number one cause ... Eg: C. burnetii ... #Infective #Endocarditis ... BloodCultures #Diagnosis #Management
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
positive in 90% of IE cases ... Septic Emboli Cause ... ↑ ESR, CRP • EKG ... Treat underlying cause ... #diagnosis #management
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
Diagnosis and Management ... infections are caused ... immunosuppression (eg ... Endophthalmitis, Endocarditis ... treatment #fungal #infectiousdiseases
Visceral Leishmaniasis - Diagnosis and Management Summary Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi Where: South Asia, East
Diagnosis and Management ... Weight Loss • Can cause ... total of 21 mg/kg ... Leishmaniasis #diagnosis #management ... #treatment #infectiousdiseases
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Culture-Negative Infective Endocarditis ... but important causes ... special stains (e.g ... Negative #Infective #Endocarditis ... differential #workup #infectiousdiseases
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Endocarditis - Overview ... Septic emboli cause ... ↑ ESR, CRP • EKG ... Treat underlying cause ... Diagnosis #cardiology #infectiousdiseases
Fusarium Treatment • Antifungal "susceptibility" can vary with Fusarium spp • F. oxysporum: low MICS to
amphotericin B for severe cases ... ; triazole (e.g. ... Fusarium #Infections #infectiousdiseases ... #management #treatment
Fusarium Infections Acquired through: 1. Inhalation of airborne conidia > germinates > blood > disseminated 2. Trauma (implantation with
BCx+ in -40% of cases ... amphotericin B for severe cases ... ; triazole (e.g. ... Fusarium #Infections #infectiousdiseases ... #diagnosis #management
Candida Glabrata Species of Candida Most Commonly Isolated in Bloodstream Infections • Symptomatic mucosal infection is detected
infections include rare cases ... of endocarditis ... candidemia #diagnosis #management ... #fungemia #management ... #infectiousdiseases
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