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diagnosis symptoms growthhormone management causes cushings differential excess feedbackloop hematology hemeonc hemophagocytic hlh hypercortisolism hypertension indications lymphohistiocytosis overproduction pituitary psychiatry
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... tissue expansion (e.g ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
risk factors (eg ... hypertension (eg ... 109 mm Hg) with clinical ... hypertension (eg ... Vasculitis • Endocrinologic
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Diagnosis and Clinical ... exposed tothe sun (e.g ... gluconeogenesis enzymes (e.g ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... renal failure Clinical ... of diagnosis (e.g ... • Heerfordt syndrome ... Diagnosis #Management #Signs
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... • Common Signs ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Serotonin Syndrome ... Pathogenesis and Clinical ... drugs of abuse (e.g ... #Pathophysiology ... Psychiatry #Diagnosis #Signs
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