8 results
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... : • Liver disease ... HUS, DIC, HELLP, AS ... #Anemia #Differential
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Grafts, Valves, AS ... Drug-associated, PCH ... Defects, Drugs, Liver ... Defects: Sickle cell anemia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
anemia • Cold ... younger pts) Differential ... Disorders Such As ... Symptoms: High fevers ... #anemia #hematology
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Non-Infectious Causes ... (Temp high in AM ... with profound hemolysis ... Brucellosis • Liver
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... glucose by the liver ... www.ncbi.nlm.nih.gov/pmc ... 30mmHg) - Severe anemia ... #Elevation #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... deficiency • Liver ... mountain spotted fever
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
infections, such as ... No hemolytic anemia ... including tests of liver ... , and possibly PCR ... #Travel #Differential
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... (elevations of liver ... Bone Marrow - Anemia ... discomfort, • +/- Hemoptysis ... NTM #Infections #differential