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differential hematology alkaline phosphatase algorithm elevation gap globulin hepatorenal hrs hrsaki hrsckd hrsnaki hus hyophosphatasia low management mds microangiopathy myelodysplasia
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
tubule of the kidney ... Most cases diagnosed ... • recurrent fractures ... : - Renal failure ... Hyophosphatasia #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Intestine - Other causes ... Intestine • Kidney ... Pregnancy - Renal ... #Algorithm #hepatology
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Syndrome (HRS) - Diagnostic ... haematuria, Normal renal ... ultrasound HRS-NAKI ... - No other cause ... HRSAKI #HRSNAKI #hepatology
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Not all MAHAs are ... TMAs cause MAHA ... /o significant renal ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... involve one, two, or all ... characteristic feature ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... musculoskeletal systems • Kidneys ... tract, and often causes ... , Elevated AST ALT ... #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Castleman disease • AL ... cancers, HCC, renal ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Males • Affects all ... seronegative) • Kidneys ... Heart failure • Renal ... Polychondritis #rheumatology ... #diagnosis #management
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