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diagnosis rheumatology treatment erythematosus hepatology lupus monoclonal nephrology oncology signs sle symptoms syndromes systemic abnormal activation agglutinin algorithm anemia arteritis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... skin injury) • Neurologic ... (Clinical Dx). ... ) Differential Diagnosis ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Monoclonal #Differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... #neurology #rheumatology ... cerebritis #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... nervous system (CNS ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
nervous system (CNS ... and less common diseases ... MRI lesions and clinical ... #neurology #noninflammatory ... #differential #
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
presence of metabolic syndrome ... alcohol-related liver disease ... non-alcoholic fatty liver disease ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Diagnosis Neurologic-Centered ... capillary leak syndrome ... Ig deposition disease ... #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... (CAS): - Due ... Viral Infection Clinical ... younger pts) Differential ... hemolytic #anemia #hematology
Hearing Loss - Differential Diagnosis Framework Hearing Loss Types: • Conductive • Sensorineural • Mixed Presbycusis is the most common type
Hearing Loss - Differential ... include a: • Neurologic ... auditory nerve (CN ... II ○ Susac’s syndrome ... ○ HIV ○ Lyme disease
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... nervous system (CNS ... • 8%-27% for CNS ... Nephrogenic DI Hematologic ... Diagnosis #Management
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