15 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal ... Coagulation Tests ... #APTT #Laboratory ... #Hematology #Diagnosis ... #Workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... versus DIL • Laboratory ... - CRP: Usually normal ... • Immunologic Workup ... Management #Summary #rheumatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Hypophostphatemia Laboratory ... Tests: - Haptoglobin ... Blood Smear ↑ abnormal ... #Diagnosis #hematology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
female, asian • Systemic ... relapse No specific laboratory ... tests: • IgG4 ... management #phenotypes #workup ... #treatment #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Remember: Systemic ... very remarkable w/differential ... , but normal values ... the “Chewing gum test ... them, but urgent rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... more time for the laboratory ... #workup #diagnosis ... #testing #Rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... value is low, tests ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... • Immunologic Workup ... months to years) Systemic ... • Immunologic Workup ... comparison #table #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... deficiency - Abnormal ... RA, Sjogren's, GPA ... deficiency Work ... Fecal occult blood test
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... and branches • GCA ... ear disease Differential ... retinopathy Lab Tests ... #diagnosis #rheumatology