10 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Fever, Arthralgia/arthritis ... Differential Diaqnoses ... • Ocular: uveitis ... #management #treatment
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
Amiodarone Toxicity ... Tremor Ataxia Ocular ... days *delays onset ... SideEffects #Adverse #Diagnosis ... #Management #Pharmacology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... low ferritin, arthritis ... synovitis (40%) Treatment ... #AdultOnset #Stills ... #management #treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... A nonpruritic macular ... Treatment - Mild ... #Stills #disease ... #rheumatology #management
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
Rheumatoid Arthritis ... marker Imaging: • XRay ... narrowing) • Ultrasound ... exam and imaging Treatment ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
sJIA) • Adult-onset ... Still disease ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Fever, cough, chills ... Cough, fever, chills ... osteoarticular, pulmonary, ocular ... Meningitis, septic arthritis ... #Management #Infections
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
initiation and onset ... skin lesions, ocular ... Zoster flare, ocular ... Fever, chills, lack ... #Management
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
and Management ... with an acute onset ... for giant cell arteritis ... universally used, ultrasound ... TREATMENT: • The
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... • Nocturnal onset ... frequent attacks • Arthritis ... not possible • Ultrasound ... #management #treatment