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diagnosis algorithm differential hepatitis injury causes blood chronic cirrhosis classification hemophagocytic hepatitisb hlh indications lfts lymphohistiocytosis oncology product reactions transaminitis
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
immunosuppression • Acute ... severe liver injury ... > 3 mg/dL) or acute ... liver failure ... #management #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Failure Infections Alcohol-Associated ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... , HBV, HCV, HEV, ... EBV, CMV), Alcohol-related ... dechallenge • Acute ... Diagnosis #Algorithm #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Diagnosis and Management ... HAV immunity; Liver ... • Liver is the ... Algorithm #Diagnosis #Management ... #Treatment #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... C, A, E, B, D, EBV ... : Alcohol, Medication ... Medication, Pregnancy, Alcoholic ... #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... , HBV, HCV, HEV, ... abnormal AST:ALT Ratios ... : • Alcoholic ... diagnosis #algorithm #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... normal - Infection (EBV ... /CMV), Alcoholic ... #Injury #hepatology
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... can be bridge to Liver ... #Algorithm #treatment ... #hepatology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... ascites removed • Acute ... #Indications #Management ... #Cirrhosis #treatment ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
hepatitis serologies, HCV ... hepatitis serologies, HCV ... ALT AST:ALT Ratios ... : • Alcoholic ... #differential #Hepatology
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