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diagnosis management syndrome tls lysis oncology pharmacology tumor deficiency differential g6pd hematology hemolysis medications druginduced elitek leukostasis table tumorlysis uricacid
Rasburicase Pharmacology Summary Recombinant urate oxidase from saccharomyces Immediate onset of action Dosing: - Package insert: 0.2 mg/kg IV
Rasburicase Pharmacology ... theABofPharmaC #Rasburicase
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
allopurinol +/- rasburicase ... phos binders - Rasburicase
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
- Allopurinol, Rasburicase
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
IV fluids • Rasburicase
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
dl, treat with Rasburicase
Drug-induced Hemolysis in G6PD Deficiency Medicines and other substances likely to be UNSAFE in moderate to severe
Primaquine - Rasburicase
Medications to Avoid in Patients with G6PD Deficiency Due to Risk of Hemolysis - Chloroquine (Aralen)*
Antimalarial Agent - Rasburicase
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