7 results
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... with MCTD and Raynaud's ... Lupusreference #Antinuclear ... #autoantibodies
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... severe disease Treatment ... #Systemic #Lupus
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... constitutional symptoms • Treatment ... months) and of autoantibodies ... • Immunologic Workup ... life-threatening • Treatment
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
with response to treatment ... serum lgE, no autoantibodies ... (antinuclear antibodies ... IgG4+ cells" Treatment ... management #phenotypes #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus (SLE) - Antinuclear ... - CCP antibody testing ... Arthritis #laboratory #workup
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
disorders • Testing ... diazepam • EMG testing ... antibody that works ... CRP • Other autoantibodies ... Person Syndrome Treatment
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... • Immunologic Workup ... constitutional symptoms • Treatment ... months) and of autoantibodies ... rheumatology #diagnosis #treatment