33 results
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... in Sickle Cell Disease ... Benefits #SickleCell #pathophysiology ... #pharmacology
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Synthesis - Renal disease ... Cardiovascular disease ... Prostaglandins #Pharmacology ... #Pathophysiology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... interstitial lung disease ... • Vascular: Raynaud's ... signs #symptoms #testing
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Disease ... Cold Agglutinin Disease ... reticularis • Raynaud ... Positive Coombs testing ... post infectious setting
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
of renal bone disease ... #Pharmacology #Pathophysiology
IDSA Recommendations for Preventing and Treating Chagas Disease (American Trypanosomiasis) in HIV-AIDS
Preventing Clinical Disease
Indication:  Individuals
Preventing and Treating ... Chagas Disease ... Treating Chagas ... Disease Note: ... infections #HIVAIDS #pharmacology
Management of Abdominal Distension and Bloating - Treatment Algorithm

Definitions
Pathophysiology
Organic/Pathologic Etiologies:
 • Small Intestinal Bowel Overgrowth (SIBO)
Definitions Pathophysiology ... Intolerance • Celiac Disease ... Diagnostics and Testing
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... moving back to resting ... Phase 4 - True Resting ... Antiarrhythmics #Pharmacology ... Classification #Classes #pathophysiology
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
Even with macular disease ... risks/benefits in setting ... Treatment #COVID19 #Pharmacology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... Proximal limb muscle wasting ... but elevated as disease ... pregnancy, Cardiac diseases ... , IgG4 related disease