11 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
block • Sjogren syndrome ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... polymyositis overlap syndrome ... Treatment: • ... Summary #diagnosis #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... : • Treatment: ... #Syndrome #Treatment ... #management #pharmacology ... #rheumatology
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
treat infectious diseases ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
Diagnosis and Testing ... positive with Histo, Fusarium ... this morphology Treatment ... vori Infectious Diseases ... #fungal #infectiousdiseases
Fusarium Treatment
 • Antifungal "susceptibility" can vary with Fusarium spp
 • F. oxysporum: low MICS to
Fusarium Treatment ... for disseminated disease ... moderate Tx in setting ... enucleation Infectious Diseases ... #Infections #infectiousdiseases
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... reticularis • Raynaud ... Positive Coombs testing ... post infectious setting ... hemolytic #anemia #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... Diagnosis via genetic testing ... • Bicytopenia Treatment ... #hematology
Fusarium Infections
Acquired through:
1. Inhalation of airborne conidia > germinates > blood > disseminated
2. Trauma (implantation with
Fusarium Infections ... , Disseminated disease ... : • Optimal treatment ... moderate Tx in setting ... #Infections #infectiousdiseases
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Cryoglobulinemia (4%-12%), Raynaud ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... #Rheumatology #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... factor (GCSF) treatments ... marrow studies Treatment ... : Goals: Treating ... #diagnosis #hematology