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hivaids idsa infections prevention diagnosis syndrome adultonset aviumcomplex capsulatum castlemans coccidiodomycosis cryptosporidiosis cytomegalovirus differential hemophagocytic hhv8 histoplasma histoplasmosis hlh immune
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... HBV, Coxsackie, CMV ... Muscular: normal CK ... #diagnosis #management ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... +: Virus (EBV, CMV ... or biologics (CMV ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
Disease: • CMV ... end-organ disease ... ART to maintain CD4 ... #management #opportunistic ... infections #HIVAIDS #pharmacology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
worsening of that disease ... previously diagnosed opportunistic ... pericarditis, peritoneal disease ... keratitis, iritis • CMV ... Differential #Diagnosis #Management
IDSA Recommendations for Preventing and Managing Cryptosporidiosis in HIV-AIDS Preventing Chronic Cryptosporidiosis: • Because chronic cryptosporidiosis occurs
should prevent the disease ... Preferred Management ... restoration to CD4 ... #management #opportunistic ... infections #HIVAIDS #pharmacology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
/aggregate) of CD4 ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
IDSA Recommendations for Preventing and Treating HHV-8 Diseases—Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL), Multicentric Castleman’s
• Since low CD4 ... recommended for KS treatment ... IDSA #Prevention #Treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Treating Coccidiodomycosis in HIV-AIDS Treating Mild Infections (Such As Focal Pneumonia or asymptomatic patients
positive serology and CD4 ... Extrathoracic Disseminated Disease ... IDSA #Prevention #Treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Managing Microsporidiosis in HIV-AIDS Preventing Chronic Microsporidiosis: • Because chronic microsporidiosis occurs
should prevent the disease ... : • The best treatment ... IDSA #Prevention #Treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
Prophylaxis: • CD4 ... Severe Disseminated Disease ... IDSA #Prevention #Treatment ... #management #opportunistic ... infections #HIVAIDS #pharmacology
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