37 results
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
cytokines Common causes ... disease Rare causes ... CD3-CD4+ T cells ... HTLVI) - Chronic inflammatory ... related disease, inflammatory
Multi-System Inflammatory Syndrome in Children (MIS-C) vs. Kawasaki Disease
CDC Case Definition for MIS-C;
 • < 21
Multi-System Inflammatory ... Kawasaki Disease CDC ... Case Definition ... for disease • Positive ... #MultiSystem #Inflammatory
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
: • Most CNS opportunistic ... • CNS opportunistic ... present in 15% of cases ... Demyelinating disease caused ... and <25% culture positive
The Cell Cycle
The cell cycle is the series of tightly regulated steps that controls cell growth
Cyclin-dependent kinases (CDKs ... Retinoblastoma (Rb ... Both Rb and p53 ... proteins) that cause ... Cyclin-dependent kinase #CDK
Causes of Polyneuropathy - Differential Diagnosis Algorithm
 • Metabolic: DM, Hypothyroidism, CKD, Cirrhosis, Nutritional deficiency
 •
Causes of Polyneuropathy ... Hypothyroidism, CKD ... Organophosphates • Inflammatory ... Diagnosis #Algorithm #causes
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... of Elevated CK ... Levels Acute CK ... Subacute to Chronic Causes ... toxoplasmosis - Inflammatory
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory ... previously diagnosed opportunistic ... with exaggerated inflammatory ... unintentional weight loss, nausea ... Reconstitution #Inflammatory
Pneumocystis jirovecii Pneumonia 
Clinical 
 • Caused by Pneumocystis jirovecii (formerly carinil) 
 • Immunocompromised host
Clinical • Caused ... • Seen in HIV positive ... patients with CD4
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Sepsis • Kidneys: CKD ... Drug/Toxin) • Inflammatory ... Differential #Diagnosis #causes
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Toxoplasmosis (CD4 ... CNS Lymphoma (CD4 ... Metastatic disease Inflammatory ... differential #diagnosis #causes