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diagnosis treatment infections differential disease hivaids idsa pharmacology prevention signs symptoms syndrome aids cytomegalovirus druginduced hiv infectiousdiseases lupus adultonset antinxp2
Cytomegalovirus (CMV) in HIV-AIDS Patients Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family. CMV infection: virus isolation or detection
Cytomegalovirus (CMV ... Cytomegalovirus (CMV ... or positive specific ... patient with HIV and CD4 ... : Esophagitis, Enteritis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Fever, Arthralgia/arthritis ... HBV, Coxsackie, CMV ... Muscular: normal CK ... Disease #diagnosis #management ... #treatment #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV-Associated CNS Opportunistic ... : • Most CNS opportunistic ... • CNS opportunistic ... - Generally >3 cm ... and <25% culture positive
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Skin lesions • Positive ... SLE, Reactive arthritis ... SLE, Reactive Arthritis ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Anti-histone - Positive ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (at least 1-2 cm ... Biopsies remain positive ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... +: Virus (EBV, CMV ... or biologics (CMV ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
previously diagnosed opportunistic ... of preexisting opportunistic ... keratitis, iritis • CMV ... • Treat for opportunistic ... Differential #Diagnosis #Management
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
Disease: • CMV ... ART to maintain CD4 ... /mm3 Managing CMV ... Prevention #Treatment #management ... #opportunistic
IDSA Recommendations for Preventing and Treating Toxoplasma gondii Encephalitis in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
Toxoplasma IgG positive ... patients with CD4 ... Prevention #Treatment #opportunistic ... infections #HIVAIDS #management
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