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diagnosis treatment differential hivaids idsa infectiousdiseases pharmacology prevention adultonset aids coccidiodomycosis cytomegalovirus fungal hemophagocytic hiv hlh immune inflammatory iris lymphohistiocytosis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... Opportunistic Infections ... : • Most CNS opportunistic ... opportunistic infections ... • CNS opportunistic
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Diaqnoses: • Infectious ... HBV, Coxsackie, CMV ... Muscular: normal CK ... #diagnosis #management ... #treatment #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... +: Virus (EBV, CMV ... or biologics (CMV ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
Disease: • CMV ... end-organ disease ... ART to maintain CD4 ... Prevention #Treatment #management ... #opportunistic
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
worsening of that disease ... pleural effusions, CNS ... pericarditis, peritoneal disease ... keratitis, iritis • CMV ... Differential #Diagnosis #Management
IDSA Recommendations for Treating Coccidiodomycosis in HIV-AIDS Treating Mild Infections (Such As Focal Pneumonia or asymptomatic patients
patients with positive ... serology and CD4 ... Extrathoracic Disseminated Disease ... Prevention #Treatment #management ... #opportunistic
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... especially the CNS ... MC: CNS CSF: • ... have positive blood ... Fungal #Diagnosis #Management
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