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treatment infections hivaids idsa prevention differential syndrome adultonset aids antinxp2 antinxp2dm cns coccidiodomycosis cytomegalovirus dermatology dermatomyositis hemophagocytic hiv hlh immune
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... HBV, Coxsackie, CMV ... Muscular: normal CK ... #diagnosis #management ... #treatment #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
- Differential Diagnosis ... cells per μL • Diagnosis ... Demyelinating disease ... - Generally >3 cm ... and <25% culture positive
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... +: Virus (EBV, CMV ... or biologics (CMV ... #management #treatment ... #summary #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
worsening of that disease ... opportunistic infection ... pericarditis, peritoneal disease ... keratitis, iritis • CMV ... #Management
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS Preventing CMV Disease: • CMV end-organ disease is best
Disease: • CMV ... ART to maintain CD4 ... Prevention #Treatment #management ... #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Treating Coccidiodomycosis in HIV-AIDS Treating Mild Infections (Such As Focal Pneumonia or asymptomatic patients
patients with positive ... Extrathoracic Disseminated Disease ... Prevention #Treatment #management ... #opportunistic ... infections #HIVAIDS #pharmacology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Diagnosis ... /aggregate) of CD4 ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
IDSA Recommendations for Preventing and Treating Varicella Zoster Virus (VZV) Infections in HIV-AIDS Pre-Exposure Prevention of VZV
patients with CD4 ... health-care provider diagnosis ... Prevention #Treatment #management ... #opportunistic ... infections #HIVAIDS #pharmacology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
NXP-2 antibody positive ... had more severe disease ... of anti-NXP-2-positive ... Dermatomyositis #diagnosis ... #management #rheumatology
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