16 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... HBV, Coxsackie, CMV ... Muscular: normal CK ... #diagnosis #management ... #treatment #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
: • Most CNS opportunistic ... • CNS opportunistic ... Demyelinating disease ... - Generally >3 cm ... and <25% culture positive
IDSA Recommendations for Preventing and Treating Chagas Disease (American Trypanosomiasis) in HIV-AIDS
Preventing Clinical Disease
Indication:  Individuals
Treating Chagas Disease ... and tested positive ... Prevention #Treatment #management ... #opportunistic ... infections #HIVAIDS #pharmacology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... +: Virus (EBV, CMV ... or biologics (CMV ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... previously diagnosed opportunistic ... pericarditis, peritoneal disease ... keratitis, iritis • CMV ... Differential #Diagnosis #Management
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 • CMV end-organ disease is best
Disease: • CMV ... ART to maintain CD4 ... Prevention #Treatment #management ... #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Preventing and Treating Toxoplasma gondii Encephalitis in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
 •
Toxoplasma IgG positive ... patients with CD4 ... Prevention #Treatment #opportunistic ... infections #HIVAIDS #management ... pharmacology
IDSA Recommendations for Treating Coccidiodomycosis in HIV-AIDS
Treating Mild Infections (Such As Focal Pneumonia or asymptomatic patients
patients with positive ... Extrathoracic Disseminated Disease ... Prevention #Treatment #management ... #opportunistic ... infections #HIVAIDS #pharmacology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... /aggregate) of CD4 ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS
Indications for Initiating Primary Prophylaxis:
 •
Prophylaxis: • CD4 ... Severe Disseminated Disease ... Prevention #Treatment #management ... #opportunistic ... infections #HIVAIDS #pharmacology