11 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... CNS Opportunistic ... • CNS opportunistic ... occur when the CD4 ... and <25% culture positive
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
Idiopathic CD4 Lymphopenia ... • Persistent CD4 ... • Infections - HIV ... #diagnosis #hematology ... #Differential #
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
ART ↑ improves CD4 ... low pretreatment CD4 ... can occur at any CD4 ... an increase in CD4 ... Depends On: • CD4
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Disease by CD4 ... Count: Any CD4 ... Seasonal influenza CD4 ... Blastomycosis CD4 ... Lymphadenopathy, CNS
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Zone Lymphoma (HCV ... Scleromyxedema (CNS ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Monoclonal #Differential
IDSA Recommendations for Treating Coccidiodomycosis in HIV-AIDS
Treating Mild Infections (Such As Focal Pneumonia or asymptomatic patients
Coccidiodomycosis in HIV-AIDS ... patients with positive ... serology and CD4 ... Pulmonary or Severely Ill ... Treatment #management #opportunistic
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Can cause TYPE IV ... /aggregate) of CD4 ... nervous system (CNS ... • 8%-27% for CNS ... Nephrogenic DI Hematologic
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... dehydrogenase • Positive ... Mycoplasma, EBV, HIV ... younger pts) Differential ... hemolytic #anemia #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Malignancy (e.g. hematologic ... and CNS • Headache ... vein thrombosis Hematologic ... La, anti-Jo-1, SCL
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
: • Syndrome of ... mucogenicum • HIV ... Advanced HIV (CD4 ... Hematologic malignancy ... NTM #Infections #differential