15 results
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
suspicion of severe disease ... splenomegaly, abnormal neurology ... , back pain Haematology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... History of bleeding (petechiae ... plateletcount), peripheral blood ... PT, aPTT(liver disease ... (CVID, WAS), (neurologic
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... inflammation, leading ... thrombosis and/or blood-brain ... Erythematosus #SLE #CNS #neurology ... #management #treatment
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
on bone marrow leading ... extramedullary disease ... Significant ↓ PLT: Petechiae ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
Marfans, EDS ... • Aortic valve disease ... ~60 • Control blood ... Aortic #Dissection #diagnosis ... #management #vascular
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... IL-1 and IL-6, leading ... mucosal bleeding (Petechial ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
work properly, leading ... caused by bleeding (petechiae ... Myeloproliferative Disease ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bleeding, and petechiae ... result from low blood ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... Manifestations of DIC: • Petechiae ... • Severe Liver Disease ... #Coagulation #diagnosis ... causes #treatment #management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Graft Versus Host Disease ... Borrellia (Lyme disease ... Trypanosoma (Chagas disease ... #Transfusions #diagnosis ... #management #hematology